Emblaveo Injection

Emblaveo Injection is specifically engineered to overcome global rise of Metallo-β-Lactamases (MBLs) has rendered many traditional antibiotics useless. The Avibactam component acts as a shield, preventing bacterial enzymes from neutralizing the Aztreonam, allowing the antibiotic to successfully destroy the bacterial cell wall.

Key Clinical Indications

• Complicated Intra-Abdominal Infections (cIAI): Used in combination with Metronidazole for deep-seated abdominal infections.

• Hospital-Acquired Pneumonia (HAP): Including Ventilator-Associated Pneumonia (VAP).

• Complicated Urinary Tract Infections (cUTI): Including cases of pyelonephritis (kidney infection).

• Limited Option Patients: Specifically for adults who have exhausted other antimicrobial treatments.

Dosage & Administration Guide

1. Preparation: Reconstitute the lyophilized powder with 10 mL of Sterile Water for Injection. Mix gently until dissolved.

2. Dilution: The reconstituted solution must be further diluted (50 mL to 250 mL) in 0.9% Sodium Chloride, 5% Dextrose, or Lactated Ringer’s.

3. Standard Adult Dose: A loading dose of 2.67 g, followed by a maintenance dose of 2 g every 6 hours.

4. Infusion Time: Administered strictly as a 3-hour slow IV infusion.

5. Renal Adjustment: Dosage must be adjusted for patients with impaired kidney function (CrCl ≤ 50 mL/min).

6. Storage: Store unconstituted vials in a refrigerator at 2°C to 8°C (36°F to 46°F) and protect from light.