Liothyronine 20mcg Tablet

Liothyronine – T3 Thyroid Hormone

Liothyronine contains Liothyronine Sodium (T3), a t3 thyroid hormone for hypothyroidism (t4 non-responders), myxoedema coma, thyroid cancer suppression, augmentation of t4. Evidence-based for DIO2 gene polymorphism patients; BTA guideline: T3 add-on when T4 monotherapy insufficient.

Product Information

People Also Ask

What is the difference between Liothyronine and levothyroxine?

Levothyroxine is T4 — a prohormone converted to active T3 in tissues, with a 7-day half-life providing stable levels. Liothyronine is the active T3 hormone with a 1-day half-life — faster onset but requiring more frequent dosing and causing greater T3 fluctuations. Most patients are managed on T4 alone; T3 is added in specific cases.

How is Liothyronine monitored?

TSH blood tests every 6–8 weeks until stable, then annually. For carbimazole: CBC monitoring for agranulocytosis. For T3: more frequent TSH monitoring due to faster T3 fluctuations.

Can Liothyronine be taken in pregnancy?

Hypothyroidism in pregnancy requires careful management — TSH targets are tighter (0.1–2.5 mU/L). Levothyroxine dose usually increases 25–30% in pregnancy. Carbimazole: use PTU in first trimester (methimazole/carbimazole avoided due to foetal abnormality risk). Liothyronine: minimal data, generally avoided in pregnancy.

What foods interact with Liothyronine?

Calcium supplements, iron, antacids, and high-fibre foods reduce levothyroxine absorption — separate by 4 hours. Soy products modestly reduce T4 absorption. Carbimazole and liothyronine have fewer food interactions but maintain consistent dosing times.

Does Liothyronine cause weight changes?

Treating hypothyroidism (levothyroxine, liothyronine): 2–5kg modest weight loss as metabolic rate normalises. Treating hyperthyroidism (carbimazole): weight gain of 2–4kg as normalised thyroid function reduces hypermetabolism.

How it works

Active T3 thyroid hormone binding nuclear receptors normalising metabolism.

Liothyronine is used for hypothyroidism (t4 non-responders), myxoedema coma, thyroid cancer suppression, augmentation of t4. Evidence-based for DIO2 gene polymorphism patients; BTA guideline: T3 add-on when T4 monotherapy insufficient. Liothyronine (T3) works faster than T4 — symptoms may improve within days, but TSH monitoring every 2–3 months is essential.

Storage

Store at 15–30°C away from sunlight and moisture. Keep out of reach of children.